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try
{
    if (!port.IsOpen && "" != port.PortName) port.Open();
}
catch (InvalidOperationException)
{
    //The specified port is open.
}
catch (ArgumentOutOfRangeException)
{
    //One or more of the properties for this instance are invalid.
    //For example, the Parity, DataBits, or Handshake properties are not valid values;
    //the BaudRate is less than or equal to zero;
    //the ReadTimeout or WriteTimeout property is less than zero and is not InfiniteTimeout.
}
catch (ArgumentException)
{
    //The port name does not begin with "COM".
    //- or -
    //The file type of the port is not supported.
}
catch (IOException)
{
    //The port is in an invalid state.
    //- or -
    //An attempt to set the state of the underlying port failed. For example, the parameters passed from this SerialPort object were invalid.
}
catch (UnauthorizedAccessException)
{
    //Access is denied to the port.
}
finally { //... }

using System;
using System.Collections.Generic;
using System.ComponentModel;
using System.Data;
using System.Drawing;
using System.Text;
using System.Windows.Forms;
using System.Threading;
using System.Net.Sockets;
using System.Net;


namespace IrDa
{
    public partial class Form1 : Form
    {
        System.IO.Ports.SerialPort sp = new System.IO.Ports.SerialPort();

        public Form1()
        {
            InitializeComponent();
            button1.Enabled = false;
            try
            {
                Cursor.Current = Cursors.WaitCursor;
               
                sp.PortName = "COM6";
                sp.BaudRate = 115200;
                sp.Parity = System.IO.Ports.Parity.None;
                sp.StopBits = System.IO.Ports.StopBits.One;
                sp.DataBits = 8;
                sp.DataReceived += new System.IO.Ports.SerialDataReceivedEventHandler(sp_DataReceived);
                sp.Open();
                button1.Enabled = true;
                Cursor.Current = Cursors.Default;
            }
            catch (Exception ex)
            {
                if (sp.IsOpen) { sp.Close(); }
                MessageBox.Show(ex.Message);
            }
        }

        void sp_DataReceived(object sender, System.IO.Ports.SerialDataReceivedEventArgs e)
        {
            label1.Text = sp.ReadExisting();
        }

        private void Form1_Closing(object sender, CancelEventArgs e)
        {
            if (sp.IsOpen) { sp.Close(); }
        }

        private void button1_Click(object sender, EventArgs e)
        {
            Cursor.Current = Cursors.WaitCursor;

            sp.WriteLine("hello");

            Cursor.Current = Cursors.Default;
        }

       
    }
}